Part 2: Health apps, wearables, and sensors: The advancing frontier of digital health

冥想
在这月初这封信上写着的地址是宾夕法尼亚大学的某个邮箱。
但是,海外机构投资者表示,随着中国经济增长放慢,香港房地产市场已经过热,正在进入调整阶段。
Manohla Dargis
4. 这事儿不能说太细。
乔斯的母亲因玛·克萨达在接受《西班牙日报》采访时表示,她的儿子想要给自己的乐队“Los Salerosos”(大意为“冒失鬼”)购买乐器。他在乐队里担任小号手。
Beauty and Evolution
However, others argued that doctors' hands may be forced by an unfair system. "As a patient, I'm more concerned about whether they can cure my illness rather than how many papers they've published," another netizen said.
IMD participants praised the way their training pushed them out of their comfort zones and also the one-on-one coaching sessions tailored to their individual business situations. “It was an eye opener about what a good leader is,” commented one participant. “We learnt about ourselves first, what drives us and why, in order to manage others.”
以下是我们精选的本届科隆游戏展最值得关注的新游戏。
3.人工胰腺
价格:197.5万元(约合人民币1264万元)
"The CPI just went up two percent year on year in 2016, less than the three-percent predictive index. It was a moderate inflation, and reflected the price level was effectively controlled and basically stable," said Jin.
中国民航局局长冯正霖表示,因天气造成航班延误的比例由2015年的29.5%增至2016年的56.8%。
supply
Belize's proximity to Mexico and the Caribbean ensures the street-food scene, providing an abundance of budget meal options.
中国疾病预防控制中心主任韩孟杰表示:“有过性经历的大学生安全套的使用率还不到40%。”
孙俪在剧中扮演女主周莹。虽然孙俪是1982年生人,但在许多观众眼中,她仍然成功塑造了一个可爱天真的少女周莹。
米尔斯在接受《每日邮报》采访中说,“《老友记》的核心是关于人要如何生活,他们想要怎样的友谊,找一份怎样的工作,以及寻找安定的不易。这些问题都是你在离开家、成长为大人、实现梦想之时所面临的。”而这也是90年代青春文化的主要内容。
圣加伦大学的表现优于上榜的其他商学院,这部分应归功于该校在国际指标上的高分。该校逾90%的学员和80%的教师来自海外。在项目期间学员国际流动性和国际交流方面,圣加伦大学都排名第二。
Comparing regions within specific categories of costs, the EIU notes that Asian cities are the most expensive for grocery shopping, with Seoul in South Korea the priciest for food. European cities are the most expensive in terms of recreation and entertainment.
That deceleration could prove a spoiler to broader growth if it continues apace, as observers have attributed sustained activity growth among manufacturers to stronger domestic demand.
Next year will be the 60th anniversary of the beloved talking bear. And to mark the occasion, Paul King, who directed 2014’s critical and commercial smash, simply titled Paddington, is back for this sequel. In a time where even children’s entertainments are suffused with darkness and violence, this quiet celebration of the everyday English is needed more than ever. The plot of this film? Well, not much really: following the events of the last film, Paddington is quite comfortably installed with the Brown family of Windsor Gardens. He wants to buy a pop-up book for his aunt from a local bookseller, but finding himself a few quid short he puts on his wellies and duffel coat and finds employment in various odd jobs – only to have the book stolen from the shop! A (not so serious) mystery begins. Expect many more jokes about Paddington’s love of marmalade. Released in the UK November 10, November 23 in Germany and November 30 in Cambodia and Malaysia. (Credit: StudioCanal)
据西藏扶贫办公室透露,位于中国西南部的西藏自治区,去年共有15万农村居民脱贫。
一些银行仍然给予股东高额回报。中国招商银行十分“大方”,其分红占净利润的30.16%。


该研究还表明,通过实习找工作或许有价值。接受录用通知的实习生的薪酬水平超过那些收到录用通知但拒绝的实习生。那些没有收到录用通知的实习生的薪酬水平更低。这些群体间的薪酬差距在毕业3年后扩大。
单词accurate 联想记忆:
下面是我对2010年美国经济以及市场前景最乐观也是最终的猜测。


With the increasing proliferation and sophistication of mobile phones, wearable devices such as smart watches, and sensors that can measure and gather a variety of data, public interest is growing in using consumer electronics to take ownership of personal health and wellness. A 2015 survey found that 66% of Americans age 66 and older want to use mobile technologies to improve their health by receiving medication reminders and tracking diet and nutrition, physical activity, and symptoms.[1

This slide in the dollar value of exports has entirely been a price effect, driven by lower commodity prices. In volume terms, emerging market exports have continued to rise since 2014, even if volume growth in year-on-year terms has moderated to around 2 per cent, a fraction of the double-digit rates witnessed either side of the global financial crisis, as the second chart shows.
Last year, the Education Ministry issued a booklet warning Korean high school students of 'plastic surgery syndrome', citing Michael Jackson and a local woman whose addiction to plastic surgery left her with a grotesquely swollen face.
Gross National Happiness
1=somewhat false

Health apps and wearables
Health apps and wearables can unobtrusively gauge physiological and emotional states and collect, quantify, and monitor data regarding a user’s day-to-day behaviors. This “quantified self” can increase users’ self-awareness regarding their behavior and encourage positive changes to their overall health and well-being.[2] These commercially available devices also integrate an array of features to provide motivation through reward systems, opportunities for social in-teraction, tools for self-improvement, and prompts. The novelty, affordability, practicality, and ease of use have resulted in increased consumer enthusiasm and the pervasiveness of these devices.[3,4] With this growing interest in personal health, members of the general public are becoming more involved in monitoring and improving their own health habits.[5-10

Undoubtedly, merely tracking data through a device is not enough to maintain good health-related behaviors long-term, and the software must also incorporate motivational constructs important for the adoption and habituation of behaviors. For instance, a systematic review of studies that considered the use of electronic activity monitor systems found short-term changes in physical activity with self-monitoring, but no demonstration of superiority when the systems were compared with other interventions.[11] Another review of studies on the viability of using mobile technology for measuring and influencing physical activity found that most apps allow users to document their activity, set goals, review real-time feedback, connect to a social support network, and access online expertise.[12] However, less common among these apps were prompts to act and opportunities for problem solving and action planning, which are crucial constructs that translate intention into long-term behavior change.[13]

Sensor technologies
Sensor technologies have begun to enter the telehealth landscape and are primarily focused on continuous monitoring and precise diagnostics to inform management of various health conditions and diseases.[14-17] Sensors can be integrated into a watch or arm band or adhesive bandages and clothing, and then programmed to collect data on cardiac rhythm, heart rate, blood pressure, respiration, oxygen saturation, galvanic skin response, glucose levels, body temperature, body motions, ambient temperature, and global positioning. For health care providers, sensor inputs can permit remote monitoring, real-time teleconferencing, and timely care for patients with chronic diseases. For both patients and clinicians, telehealth supported by sensors can have profound implications. Clinicians can provide timely and patient-centred care to those living at a distance with chronic disease and can coordinate care when multiple providers are involved, reducing costs to the health care system.

A current clinical example is the management of paroxysmal atrial fibrillation with a mobile ECG and app that monitors the patient’s electrical rhythm to detect frequency and patterns of arrhythmias, and may even allow patients to share ultrasound and electrocardiogram data with their health care provider.[18-20] Telemonitoring with sensors can also support self-management of chronic diseases and detect early signs of deterioration in health requiring immediate treatment and advice.[21] Studies to date have demonstrated some clinical promise for the use of home telemonitoring in the context of heart failure and diabetes. A recent Cochrane review found that telemonitoring was an effective way to lower levels of glycated hemoglobin and low-density lipoprotein.[22] Although several studies on heart failure have produced conflicting results regarding the overall benefits of home monitoring,[23-26] systematic reviews have suggested that home telemonitoring reduces all-cause mortality and hospitalizations, and improves quality of life compared with usual care.[22,27] In addition, features such as automated and mobile telemonitoring appear to be more effective compared with other forms of home telemonitoring.[27]

Further studies are needed to determine how home health monitoring can improve patient safety during the transition from acute care to community care, and to examine the impact of home monitoring on health care costs. TEC4Home (Telehealth for Emergency-Community Continuity of Care Connectivity via Home Tele-monitoring), an initiative of the University of British Columbia and Vancouver Coastal Health, is seeking to do this with prospective trials designed to uncover how telemonitoring can support the safety of heart failure patients discharged from hospital to home.[28]

Mobile apps, wearables, and sensors in the clinical setting
Even though mobile apps, wearables, and sensor technologies are promising, further research is needed to validate their use and long-term impact.[29] This research will require the collaboration of clinicians, health researchers, engineers, and computer scientists.[30] Understanding the possible risks of using these technologies, from physiological harm to breaching of privacy and confidentiality with insecure devices, and how to mitigate any risks is also important. Other important issues to consider include patient anxiety with overuse of technologies, health data piracy, self-diagnosis resulting from overreliance on self-monitoring, and patients not seeking help appropriately. These technologies should be used only as complementary tools in the treatment and prevention of health conditions and disease and should not be used in isolation by patients who self-diagnose and self-manage without consulting a health professional. 

扎克伯格还协助成立了一个名为FWD.us的游说团体,旨在推动美国的移民和教育改革。

Instant Heart Rate by Azumio.[31] A free app downloadable to both Apple and Android operating systems that measures heart rate and displays a monitoring strip. As well as helping users accurately track their heart rates, the app is capable of detecting irregular rhythms when palpitations occur. 

Sleep Time by Azumio.[32] A free app that monitors sleep patterns, sleep efficiency, and also acts as an alarm clock. Users can know how often they go into light and deep sleep, and recognize how much of these types of sleep will be necessary for them to feel rested, thereby quantifying the amount of true sleep they need and not just how long they should stay in bed. 

Bellybio Interactive Breating by RelaxLine.[33] A free app that helps users pace their breathing to achieve calmness. Placing the mobile phone against the abdomen, users can follow the sounds emitted to practise deep, abdominal breathing using this simple yet surprisingly effective tool. 

‘The Mindy Project’ It doesn’t matter that Mindy Kaling’s comedy on Fox is in its third season and still not a hit, because it keeps improving with age. It has grown from a one-comedian showcase into a very funny ensemble effort, thanks in part to the addition of Adam Pally in Season 2 and jokes about Ms. Kaling’s alma mater, Dartmouth.
Wang studied computer programming while growing up in China. After college, she hoped to move to the U.S. to start her career. The next year, the Chinese Students Protection Act was passed and Wang got her master's in computer science at University of Houston. She worked at several Silicon Valley startups (and launched her own, iBizWomen.com) until September 11, 2001. The attack inspired her to create Binary Group, a technology consulting company that works with the Federal Government. Over the past 16 years, Binary has helped its clients save piles of money -- like the Army 20th Support Command, which cut $60 million over five years for its satellite communication bandwidth requirements.

Misrepresenting your credentials or intentionally plagiarizing, lying on time sheets or billable hours, misusing expense accounts or abusing company credit cards, stealing the kudos for a co-workers' accomplishments, or otherwise robbing your employers blind can all cost you your job.
近些年来,细菌感染卷土重来,受害者达到了自1960s以来从所未见的最高值,初步确诊者的人数从429跃升至1300多人,从2011年到2017年期间的感染人数翻了两倍不止。
上周五,中国汽车制造协会宣布,1月份的乘用车销量达到220万台,比去年同期增长了9.3%,同时,新能源汽车的产量则激增了144%。
Mr Williams notes that early November data from the likes of Brazil, Vietnam, Taiwan and Chile suggests the picture has continued to improve since October.
7. “The Kindergarten Teacher” In his tough, weird knockout, the Israeli director Nadav Lapid spins the story of a teacher’s obsession with a child poet to create a savage portrait of fanaticism and its costs.
United States emissions had been declining because of increased burning of natural gas in power generation, which emits less carbon dioxide for each unit of energy than does coal. But the nation reported an increase in 2013 as coal regained some market share. If that trend continues, it could prove to be a challenge for the Obama administration as it seeks to institute tighter policies on greenhouse gases.

Discernment to determine whether a particular app, wearable, or sensor can be effective.
Expertise and experience to guide patients on the use of technology.
Partnership with patients in pursuit of optimal health through technology use.
Trials to closely monitor benefits and drawbacks.
Humility to recognize that patients may know and invest much more time than physicians in looking for these tools.34

Conclusions
Based on today’s rapid pace of development and public enthusiasm for the technology marketplace, health apps, wearables, and sensors will soon become integral to our patients’ pursuits of good health and will need to be integrated in clinical practice. Physicians must be active agents in these evolutionary times, guiding patients, advocating for evidence to support the use of technologies, and participating in the development and incorporation of technology in patient wellness journeys. Through clinical stewardship and partnership with patients, physicians can use their expertise and experience to guide the growth of innovations into mainstream health care.

Competing interests
Dr Ho receives no personal financial compensation as the principal investigator of TEC4Home (Telehealth for Emergency-Community Continuity of Care Connectivity via Home Tele-monitoring), a project funded by a Canadian Institutes of Health Research grant. This grant is matched by the Michael Smith Foundation for Health Research and the BC Ministry of Health, with additional support provided by TELUS Health and Sentrian. TELUS Health, Cisco, and Avizia have also provided equipment for display in Dr Ho’s Demonstration and Simulation Studio for Health (DaSSH) at UBC. Mr Yao and Dr Lauscher have no competing interests to declare.


毛盛勇:降税减费政策将对制造业增长形成政策支撑


References

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2. Swan M. Emerging patient-driven health care models: An examination of health social networks, consumer personalized medicine and quantified self-tracking. Int J Environ Res Public Health 2009;6:492-525.

3. Gao Y, Li H, Luo Y. An empirical study of wearable technology acceptance in healthcare. Ind Manag Data Syst 2010;115:1704-1723.

4. Kim KJ, Shin DH. An acceptance model for smart watches: Implications for the adoption of future wearable technology. Internet Res 2015;25:527-541.

5. West JH, Hall PC, Hanson CL, et al. There’s an app for that: Content analysis of paid health and fitness apps. J Med Internet Res 2012;14:e72.

6. Abroms LC, Padmanabhan N, Thaweethai L, Phillips T. iPhone apps for smoking cessation: A content analysis. Am J Prev Med 2011;40:279-285.

7. Cowan LT, Van Wagenen SA, Brown BA, et al. Apps of steel: Are exercise apps providing consumers with realistic expectations? A content analysis of exercise apps for presence of behavior change theory. Health Educ Behav 2013;40:133-139.

8. Azar KM, Lesser LI, Laing BY, et al. Mobile applications for weight management. Am J Prev Med 2013;45:583-589.

9. Breland JY, Yeh VM, Yu J. Adherence to evidence-based guidelines among diabetes self-management apps. Transl Behav Med 2013;3:277-286.

10. Lyons EJ, Lewis ZH, Mayrsohn BG, Rowland JL. Behavior change techniques implemented in electronic lifestyle activity monitors: A systematic content analysis. J Med Internet Res 2014;16:e192.

11. Lewis ZH, Lyons EJ, Jarvis JM, Baillargeon J. Using an electronic activity monitor system as an intervention modality: A systematic review. BMC Public Health 2015;15:585.

12. Bort-Roig J, Gilson ND, Puig-Ribera A, et al. Measuring and influencing physical activity with smartphone technology: A systematic review. Sports Med 2014;44:671-686.

13. Rhodes RE, Yao CA. Models accounting for intention-behavior discordance in the physical activity domain: A user’s guide, content overview, and review of current evidence. Int J Behav Nutr Phys Act 2015;12:1-14.

14. Chen M, Gonzalez S, Vasilakos A, et al. Body area networks: A survey. Mob Networks Appl 2011;16:171-193.

15. Appelboom G, Camacho E, Abraham ME, et al. Smart wearable body sensors for patient self-assessment and monitoring. Arch Public Health 2014;72:28.

16. Chan M, Estève D, Fourniols JY, et al. Smart wearable systems: Current status and future challenges. Artif Intell Med 2012;56:137-156.

17. Alemdar H, Ersoy C. Wireless sensor networks for healthcare: A survey. Comput Networks 2010;54:2688-2710.

18. Haberman ZC, Jahn RT, Bose R, et al. Wireless smartphone ECG enables large-scale screening in diverse populations. J Cardiovasc Electrophysiol 2015;26:520-526.

19. Ferdman DJ, Liberman L, Silver ES. A smartphone application to diagnose the mechanism of pediatric supraventricular tachycardia. Pediatr Cardiol 2015;36:1452-1457.

20. Baquero GA, Banchs JE, Ahmed S, et al. Surface 12 lead electrocardiogram recordings using smart phone technology. J Electrocardiol 2015;48:1-7.

21. Wootton R. Twenty years of telemedicine in chronic disease management—An evidence synthesis. J Telemed Telecare 2012;18:211-220.

22. Flodgren G, Rachas A, Farmer A, et al. Interactive telemedicine: Effects on professional practice and health care outcomes. Cochrane Database System Rev 2015;(9):CD002098.

23. Mortara A, Pinna GD, Johnson P, et al. Home telemonitoring in heart failure patients: The HHH study (Home or Hospital in Heart Failure). Eur J Heart Fail 2009;11:312-318.

24. Dar O, Riley J, Chapman C, et al. A randomized trial of home telemonitoring in a typical elderly heart failure population in North West London: Results of the Home-HF study. Eur J Heart Fail 2009;11:319-325.

25. Chaudhry SI, Mattera JA, Curtis JP, et al. Telemonitoring in patients with heart failure. N Engl J Med 2010;363:2301-2309.

26. Koehler F, Winkler S, Schieber M, et al. Impact of remote telemedical management on mortality and hospitalizations in ambulatory patients with chronic heart failure: The Telemedical Interventional Monitoring in Heart Failure study. Circulation 2011;123:1873-1880.

27. Kitsiou S, Pare G, Jaana M. Effects of home telemonitoring interventions on patients with chronic heart failure: An overview of systematic reviews. J Med Internet Res 2015;17:e63.

28. TEC4Home Healthcare Innovation Community. Supporting heart failure patient transitions from acute to community care with home telemonitoring technology: A protocol for a provincial randomized controlled trial (TEC4Home). JMIR Res Protoc 2016;5:e198. 

29. Yao C, Ho K. Mobile sensors and wearable technologies. In: Amelung VE, Stein V, Goodwin N, et al., editors. Handbook integrated care. Cham, Switzerland: Springer; 2017.

30. Ho K, Borycki E, Kushniruk A, et al. The health perspective in using digital media for health and wellness. Presented at the IEEE International Digital Media Industry Forum, Boston, MA, 4-6 July 2016.

31. Azumio Inc. Instant heart rate. Accessed 28 August 2017. www.azumio.com/s/instantheartrate/index.html. 

32. Azumio Inc. Sleep time. Accessed 28 August 2017. www.azumio.com/s/sleeptime/index.html. 

33. RelaxLine. BellyBio. Accessed 28 August 2017. https://itunes.apple.com/ca/app/bellybio-interactive-breathing/id353763955?mt=8.

34. Ho K. How health information technologies are enhancing health of patients and their doctors. Presentation at the Alberta Medical Association 2015 Spring Representatives Forum, Edmonton, AB, 13 March 2015.


面试官也会犯错:
IT富豪榜排名前十的富豪的平均年龄为45岁,现年52岁的马云是其中年纪最大的一位。
Ranked fourth with 15.27 million visitors, Dubai "made a quantum leap to become the global top-ranked" in visitor spending, the report says.
"To make the world a better place, I invented a transformative water purifier," Google quoted Zhang as saying. "It takes in dirty and polluted water from rivers, lakes and even oceans, then massively transforms the water into clean, safe and sanitary water. When humans and animals drink this water, they will live a healthier life."
Farewell to Cassini
美国太空探索技术公司取得了一项令人难以置信的成就。“猎鹰9号”发射器的一级火箭在成功将货物运送到国际空间站后,能够自主转向,释放了主发动机燃烧提供的巨大动能,飞回地球并垂直降落在漂浮在大西洋上的一艘相当小的自动驳船上,极其精准。
Online registration for the 2017 national civil servant exam started last Saturday.
在不久的将来,罗根(休?杰克曼饰)已迈入暮年。他在墨西哥边境附近的一个藏身所里照顾着重病的X教授(帕特里克?斯图尔特饰)。他计划隐世度日,但他遇见了一个非常像他的年轻变异人劳拉(达芙妮?基恩饰)后,这个计划搁置了。罗根必须保护这个女孩,与要捕杀她的黑暗势力斗争。
王斌表示,去年母婴传播率也达到了历史最低点,从2012年的7.1%下降到2017年的4.9%。
The banks' ability to return money to shareholders have declined. The slowing earning growth, high nonperforming loans and required deposits on the reserve have placed pressure on the banks in regards to capital supplement, said Guo Tianyong, director of the China Banking Research Center at the Central University of Finance and Economics.

Kendall Ho, MD, FRCPC, Christopher Yao, MSc, Helen Novak Lauscher, PhD. Part 2: Health apps, wearables, and sensors: The advancing frontier of digital health. BCMJ, Vol. 59, No. 10, December, 2017, Page(s) 503-506 - Clinical Articles.



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A best film nomination looks certain. Darkest Hour's Gary Oldman is the favorite for best actor, but if anyone can beat him it's probably Chalamet.
5) I’ve Got Your Back: We’ve all made big mistakes. In those times, step in with a reassurance: “I’m not judging you. You’re going to get through this. You’re not alone. We’ll figure this out together. It’s going to be OK.”
关于7月9日的枪击案,调查人员已逮捕两名年轻人,其中一名18岁。
I once had an advisor that said to me when I expressed fear of a difficult class, "Do you want to get an education or not?"

My arms are wide open for you this New Year.我张开双臂,盼与你共度新春佳节。

  • Only the first three authors are listed, followed by "et al."
  • 北京首批限房价项目获批入市 短期入市房源有望超2万套
  • 家居业掀“自制标准”风:衣柜业重在落实


The charges of Russian hacking and Mr Trump’s evident defects of experience, judgment and character show that the college has not proved the bulwark Mr Hamilton hoped for.
Interviewers made their share of blunders, too.

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